Helicobacter pylori

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Neglecting Helicobacter pylori Infection Raises the Risk of Stomach Cancer: Combination Drug Therapy Provides Effective Treatment

In Hong Kong, one in every two people is infected with Helicobacter pylori. This bacterium lurks in our stomachs and can trigger chronic gastritis, with long-term inflammation potentially leading to stomach ulcers and even stomach cancer. The World Health Organization has classified it as a Group 1 carcinogen, so it cannot be left untreated in the stomach. Dr. NG Sui Cheung, a specialist in Gastroenterology and Hepatology at Chiron Medical, will explore Helicobacter pylori and its implications for early prevention, identification, and management.

Understanding Risk Factors and Symptoms: Key to Identifying Infection

Dr. Ng notes that several factors may increase the risk of Helicobacter pylori infection, including a history of stomach ulcers, frequent indigestion, a family history of stomach cancer, smoking, and being over 40 years old. Additionally, individuals who share meals with those infected have a relatively higher risk of infection.

Infected individuals often show no obvious symptoms, and many may only discover their condition during routine check-ups. However, if symptoms such as stomach pain or loss of appetite occur, prompt medical attention is necessary. Diagnostic methods include the carbon-13 breath test, gastroscopy with biopsy, stool antigen tests, and serum antibody tests, each with its advantages and limitations. Doctors will choose the most appropriate testing method based on the patient's specific situation.

Treatment Options and Follow-Up Frequency Vary by Individual

The primary treatment for Helicobacter pylori infection is triple therapy, which includes a proton pump inhibitor and two antibiotics, typically lasting for 14 days. After completing the treatment, patients should undergo a breath test six weeks later to ensure that the bacteria have been eradicated.

If the first treatment is ineffective, a quadruple therapy may be necessary for more effective bacterial elimination. After treatment, patients need regular follow-ups to monitor their stomach health and ensure the condition does not recur. The specific frequency of check-ups depends on individual health status and risk factors, so it is advisable to discuss an appropriate follow-up plan with a doctor.

Cultivating Daily Habits for Health Protection

Dr. Ng reminds us that the most important preventive measure against Helicobacter pylori infection is maintaining good personal hygiene, washing hands frequently, and being mindful of food safety. Additionally, using serving chopsticks and ensuring clean water sources are effective preventive strategies. Developing a habit of regular health check-ups is also essential for proactively managing one's health status.

 

Method

Accuracy Rate

Advantages

Limitations

Carbon-13 Breath Test

90%+

Non-invasive, quick

Requires stopping antibiotics or
acid suppressants for 2 to 4 weeks

Gastroscopy + Biopsy

95%+

Directly identifies
abnormalities

Invasive / high cost

Stool Antigen Test

85%+

Suitable for children

Sample processing is complex

Serum Antibody Test

70-80%

Quick screening

Cannot distinguish current infection
from past infection


Updated: 2025-07

Please note that all medical health articles featured on our website have been reviewed by Chiron Medical doctors. The articles are for general information only and are not medical opinions nor should the contents be used to replace the need for personal consultation with a qualified health professional on the reader's medical condition.